BDBM560279 US11377439, Example 116

SMILES CC(C)(C)C(=O)CNS(=O)(=O)c1ccc(cc1)C(=O)N[C@H](CC1CCCCC1)C(=O)N1C[C@H](C[C@H]1C(=O)NC1(CCSCC1)C(=O)C(N)=O)n1nncc1C(C)(C)O

InChI Key InChIKey=KAEHJALGISFJEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560279   

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM560279(US11377439, Example 116)
Affinity DataIC50: 4nMAssay Description:Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
Go to US Patent