BDBM559922 5-fluoro-2-isopropyl-N-(4-methyl-3-(5- morpholino-6-(prop-1-yn-1-yl)pyridin-3- yl)phenyl)isonicotinamide::US11377431, Example 34

SMILES CC#Cc1ncc(cc1N1CCOCC1)-c1cc(NC(=O)c2cc(ncc2F)C(C)C)ccc1C

InChI Key InChIKey=KKHFEPXKYSICTI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559922   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent

LigandBDBM559922(US11377431, Example 34 | 5-fluoro-2-isopropyl-N-(4...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Small molecule inhibition of the BRA and RAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/5/2022
Entry Details
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