BDBM559909 N-(3-{6-[(3S)-3-Hydroxybut-1-yn-1-yl]- 5-(morpholin-4-yl)pyridin-3-yl}-4- methylphenyl)-2- (trifluoromethyl)pyridine-4-carboxamide::US11377431, Example 21

SMILES C[C@@H](O)C#Cc1ncc(cc1N1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=CAQXRXGGPCVHJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559909   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM559909(US11377431, Example 21 | N-(3-{6-[(3S)-3-Hydroxybu...)
Affinity DataIC50: 1nMAssay Description:Small molecule inhibition of the BRA and RAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test ...More data for this Ligand-Target Pair
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Date in BDB:
10/5/2022
Entry Details
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