BDBM559898 N-(4-methyl-3-{2-[3-(methylamino)prop- l-yn-1-yl]-6-(morpholin-4-yl)pyridin-4- yl}phenyl)-2-(trifluoromethyl)pyridine- 4-carboxamide::US11377431, Example 10

SMILES CNCC#Cc1cc(cc(n1)N1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=XRFDLRXEGDAGKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559898   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM559898(US11377431, Example 10 | N-(4-methyl-3-{2-[3-(meth...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRA and RAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test ...More data for this Ligand-Target Pair
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Date in BDB:
10/5/2022
Entry Details
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