BDBM559895 N-(4-methyl-3-[2-(morpholin-4-yl)-6-[3- (pyrrolidin-1-yl)prop-1-yn-1-yl]pyridin- 4-yl]phenyl}-2- (trifluoromethyl)pyridine-4-carboxamide::US11377431, Example 9

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(nc(c1)N1CCOCC1)C#CCN1CCCC1

InChI Key InChIKey=VHZBBTUTYBYYNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559895   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM559895(US11377431, Example 9 | N-(4-methyl-3-[2-(morpholi...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRA and RAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test ...More data for this Ligand-Target Pair
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Date in BDB:
10/5/2022
Entry Details
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