BDBM559889 N-[3-[2-(3-hydroxyprop-1-yn-1-yl)-6- (morpholin-4-yl)pyridin-4-yl]-4- methylphenyl]-2- (trifluoromethyl)pyridine-4-carboxamide::US11377431, Example 4

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(nc(c1)N1CCOCC1)C#CCO

InChI Key InChIKey=WLLLKVQLWHUZMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559889   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM559889(US11377431, Example 4 | N-[3-[2-(3-hydroxyprop-1-y...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRA and RAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test ...More data for this Ligand-Target Pair
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Date in BDB:
10/5/2022
Entry Details
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