BDBM559801 WO2022109182, Example 32

SMILES COCCn1c(C[C@H]2CC[C@@H](CC2)c2cccc(OCc3ccc(cc3F)C#N)n2)nc2c(cc(cc12)C(O)=O)-c1ccn(C)n1

InChI Key InChIKey=YYZQZEFSDWPOPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559801   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559801(WO2022109182, Example 32)
Affinity DataIC50: 11nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182