BDBM559799 2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyridyl]-1-piperidyl]methyl]-6-(1-methylpyrazol-3-yl)-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic acid::WO2022109182, Example 30

SMILES Cn1ccc(n1)-c1cc2nc(CN3CCC(CC3)c3cccc(OCc4ccc(cc4F)C#N)n3)n(C[C@@H]3CCO3)c2cc1C(O)=O

InChI Key InChIKey=HRQACMLHJQHVGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559799   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559799(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyri...)
Affinity DataIC50: 52nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182