BDBM559792 WO2022109182, Example 23

SMILES OC(=O)c1cc(F)c2nc(CN3CCN(CC3)c3cccc(OCc4ccc(cc4F)C#N)n3)n(C[C@@H]3CCO3)c2c1

InChI Key InChIKey=MLKPXLROMPLJTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559792   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559792(WO2022109182, Example 23)
Affinity DataIC50: 0.0300nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182