BDBM559783 2-(6-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)-6-azaspiro[2.5]octan-1-yl)-1-(2-methoxyethyl)-1H-benzo[d]imidazole-6-carboxylic acid::WO2022109182, Example 14

SMILES COCCn1c(CN2CCC(CC2)c2cccc(OCc3ccc(cc3F)C#N)n2)nc2c(F)cc(cc12)C(O)=O

InChI Key InChIKey=BFSAIYIDXRSVBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559783   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559783(2-(6-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)...)
Affinity DataIC50: 1.04nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182