BDBM559781 WO2022109182, Example 12

SMILES CC(C)(O)C#Cc1cc(cc2n(C[C@@H]3CCO3)c(CN3CCC(CC3)c3cccc(OCc4ccc(cc4F)C#N)n3)nc12)C(O)=O

InChI Key InChIKey=GAOCXUNFCLOKSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559781   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559781(WO2022109182, Example 12)
Affinity DataIC50: 0.810nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182