BDBM559653 US11370803, Compound I-18

SMILES Fc1c(Cl)ccn2cnc(CNCc3cn(Cc4cn5cc(cc(-n6cnnc6)c5n4)C4CC4)nn3)c12

InChI Key InChIKey=FFPGMRIUTFIZQG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559653   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559653(US11370803, Compound I-18)
Affinity DataEC50: <50nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent