BDBM559650 US11370803, Compound I-16

SMILES Fc1c(Cl)ccn2cnc(CNC(c3cnn(Cc4cn5cc(ccc5n4)C4CC4)c3)C(F)(F)F)c12

InChI Key InChIKey=MBBPCKSVOTVUHF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559650   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559650(US11370803, Compound I-16)
Affinity DataEC50: <50nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent