BDBM559648 US11370803, Compound I-14

SMILES COC(=O)c1cc(cn2cc(Cn3cc(CNCc4ncn5ccc(Cl)c(F)c45)nn3)nc12)C1CC1

InChI Key InChIKey=FXHTURBYHYMVQU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559648   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559648(US11370803, Compound I-14)
Affinity DataEC50: <50nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent