BDBM559642 US11370803, Compound I-8

SMILES Fc1c(Cl)ccn2cnc(CNC(=O)c3cn4C(CCc4n3)c3cn4cc(ccc4n3)C3CC3)c12

InChI Key InChIKey=YSKJNXYWJODTSB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559642   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559642(US11370803, Compound I-8)
Affinity DataEC50: <50nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent