BDBM559638 US11370803, Compound I-4

SMILES Fc1c(Cl)ccn2cnc(CNS(=O)(=O)c3cnn(Cc4cn5cc(ccc5n4)C4CC4)c3)c12

InChI Key InChIKey=PWYRIOSQAKLGMA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559638   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559638(US11370803, Compound I-4)
Affinity DataEC50:  600nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent