BDBM559636 US11370803, Compound I-2

SMILES Fc1c(Cl)ccn2cnc(C(NCc3cn(Cc4cn5cc(ccc5n4)C4CC4)nn3)C(F)(F)F)c12

InChI Key InChIKey=IHZMHBCITXJBHK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559636   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559636(US11370803, Compound I-2)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent