BDBM559478 US11370779, Compound 46

SMILES COc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\OCCN3CCNCC3)c2c1

InChI Key InChIKey=IZGPBQGCVURPGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559478   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559478(US11370779, Compound 46)
Affinity DataIC50: 12.4nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent