BDBM559476 US11370779, Compound 44

SMILES FC(F)(F)Oc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\OCCN3CCNCC3)c2c1

InChI Key InChIKey=FNYRHYHVDYNRKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559476   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559476(US11370779, Compound 44)
Affinity DataIC50: 40.2nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent