BDBM559460 BDBM50564368::US11370779, Compound 28

SMILES O=C1Nc2ccccc2\C1=C1\Nc2ccccc2\C\1=N/OCCN1CCNCC1

InChI Key InChIKey=ULNQWYGVWVDLPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 559460   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM559460(US11370779, Compound 28 | BDBM50564368)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM559460(US11370779, Compound 28 | BDBM50564368)
Affinity DataIC50: 2.70nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM559460(US11370779, Compound 28 | BDBM50564368)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed