BDBM559456 US11370779, Compound 24

SMILES Fc1ccc2N\C(\C(=N\OCCN3CCCC3)\c2c1)=C1/C(=O)Nc2ccc(F)cc12

InChI Key InChIKey=BGZJJZINPAHWTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559456   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559456(US11370779, Compound 24)
Affinity DataIC50: 116nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent