BDBM559455 US11370779, Compound 23

SMILES Fc1ccc2N\C(\C(=N\OCCN3CCCCC3)\c2c1)=C1/C(=O)Nc2ccc(F)cc12

InChI Key InChIKey=IHTAIMPVCGZTAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559455   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559455(US11370779, Compound 23)
Affinity DataIC50: 45nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent