BDBM559439 US11370779, Compound 7

SMILES O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(cc12)C(O)=O

InChI Key InChIKey=CBUBUEVQMMYUGL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 559439   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559439(US11370779, Compound 7)
Affinity DataIC50: 8nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559439(US11370779, Compound 7)
Affinity DataIC50: 7.89E+3nMAssay Description:Inhibition of recombinant FLT3 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Pelemed

US Patent
LigandPNGBDBM559439(US11370779, Compound 7)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed