BDBM558896 US11370774, Compound 14c::US11708347, Compound 14c

SMILES CCOC(=O)Cc1ccccc1NC(=O)c1cc(-c2cccc(CN)c2)c2cc[nH]c2n1

InChI Key InChIKey=FYKBONILBHTEKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558896   

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM558896(US11370774, Compound 14c | US11708347, Compound 14...)
Affinity DataIC50: 1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM558896(US11370774, Compound 14c | US11708347, Compound 14...)
Affinity DataIC50: 1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used. For this assay Z-Lys-SBzl, 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent