BDBM558581 (R)-6-(2-chloro-3,5-dimethoxyphe- nyl)-N-(4-(hexahydropyrazino[2,1- c][1,4]oxazin-8(1H)-yl)phenyl)- [1,2,4]triazolo[4',3':1,6]pyrido[2,3- d]pyrimidin-2-amine::US11365196, Compound 43

SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(Nc3ccc(cc3)N3CCN4CCOC[C@H]4C3)nc2n2cnnc12

InChI Key InChIKey=KEFBKOMBWOFTFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558581   

TargetFibroblast growth factor receptor 1(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM558581((R)-6-(2-chloro-3,5-dimethoxyphe- nyl)-N-(4-(hexah...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of some compounds of the present disclosure against FGFR1, FGFR2, FGFR3, FGFR4, KDR was tested by mobility shift assay (conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent