BDBM558188 1-Acetyl-4-[8-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]oxy]octyl]-4-piperidinecarboxylic Acid::US11365192, Example 6-1

SMILES CC(=O)N1CCC(CCCCCCCCOc2ccc(nc2)-c2ccn[nH]2)(CC1)C(O)=O

InChI Key InChIKey=CDFRSZGNALIDGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558188   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558188(US11365192, Example 6-1 | 1-Acetyl-4-[8-[[6-(1H-py...)
Affinity DataIC50: 7.90nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558188(US11365192, Example 6-1 | 1-Acetyl-4-[8-[[6-(1H-py...)
Affinity DataIC50: 770nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent