BDBM557943 N-Methyl-4-({2-[(trans)-4-[4-fluoro-2-(trifluoromethyl)phenyl]cyclohexyl]ethyl}amino)oxane-4-carboxamide::US11365191, Example 46

SMILES CNC(=O)C1(CCOCC1)NCC[C@H]1CC[C@H](CC1)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=BEYMYJIZPYZATG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557943   

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557943(N-Methyl-4-({2-[(trans)-4-[4-fluoro-2-(trifluorome...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent