BDBM557940 4-((2-((trans)-4-(2,4-difluoro-6-methylphenyl)cyclohexyl)ethyl)amino)tetrahydro-2H-pyran-4-carboxamide::US11365191, Example 42

SMILES Cc1cc(F)cc(F)c1[C@@H]1CC[C@H](CCNC2(CCOCC2)C(N)=O)CC1

InChI Key InChIKey=OUTIEQVLODSYCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557940   

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557940(4-((2-((trans)-4-(2,4-difluoro-6-methylphenyl)cycl...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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