BDBM557841 US11365185, Example 23B

SMILES CC(C)c1cncc(Nc2c(cnn2C)-c2ccc(cn2)-c2ccc(nc2)C2(CC2)C(O)=O)n1

InChI Key InChIKey=RDHJKFCYDGUKLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557841   

TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557841(US11365185, Example 23B)
Affinity DataIC50: 111nMAssay Description:A cDNA encoding the human LPAR1 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U937 cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetLysophosphatidic acid receptor 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM557841(US11365185, Example 23B)
Affinity DataIC50: 1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent