BDBM557770 1-[4-[6-[5-[(6-tert-butoxypyrazin-2-yl)amino]-1-methyl-pyrazol-4-yl]-3-pyridyl]phenyl]cyclopropanecarboxylic Acid::US11365185, Example 1B

SMILES Cn1ncc(c1Nc1cncc(OC(C)(C)C)n1)-c1ccc(cn1)-c1ccc(cc1)C1(CC1)C(O)=O

InChI Key InChIKey=AYMKOPYHGWQBBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557770   

TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM557770(US11365185, Example 1B | 1-[4-[6-[5-[(6-tert-butox...)
Affinity DataIC50: 74.4nMAssay Description:A cDNA encoding the human LPAR1 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U937 cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetLysophosphatidic acid receptor 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM557770(US11365185, Example 1B | 1-[4-[6-[5-[(6-tert-butox...)
Affinity DataIC50: 1.33E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent