BDBM557375 US11352356, Compound I-37

SMILES O=C(NCc1ncn2ccc(Br)cc12)c5cnn(Cc4cn3cc(Br)c(Cl)cc3n4)c5

InChI Key InChIKey=UDFPEIWDWQLTKO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557375   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM557375(US11352356, Compound I-37)
Affinity DataEC50:  55nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent