BDBM55734 (5Z)-2,6-diketo-4-methyl-5-(m-tolylhydrazono)nicotinonitrile::(5Z)-4-methyl-5-[(3-methylphenyl)hydrazinylidene]-2,6-bis(oxidanylidene)pyridine-3-carbonitrile::(5Z)-4-methyl-5-[(3-methylphenyl)hydrazinylidene]-2,6-dioxo-3-pyridinecarbonitrile::(5Z)-4-methyl-5-[(3-methylphenyl)hydrazinylidene]-2,6-dioxopyridine-3-carbonitrile::6-hydroxy-4-methyl-5-[(3-methylphenyl)diazenyl]-2-oxo-1,2-dihydro-3-pyridinecarbonitrile::MLS000704357::SMR000231531::cid_11839138

SMILES CC1=C(C#N)C(=O)NC(=O)C1=NNc1cccc(C)c1

InChI Key InChIKey=IZJIWBDMFLYDAE-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 55734   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM55734((5Z)-4-methyl-5-[(3-methylphenyl)hydrazinylidene]-...)
Affinity DataEC50:  775nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM55734((5Z)-4-methyl-5-[(3-methylphenyl)hydrazinylidene]-...)
Affinity DataIC50: 5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM55734((5Z)-4-methyl-5-[(3-methylphenyl)hydrazinylidene]-...)
Affinity DataEC50:  2.59E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay