BDBM557105 (R)-(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 3,4'-bipyridin- 5-yl)(3-::US11352340, Example 155

SMILES Cc1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)C(=O)N1CC[C@@H](F)C1

InChI Key InChIKey=CVPMIIYGQDFEPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557105   

LigandPNGBDBM557105((R)-(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 3,4'-bi...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

LigandPNGBDBM557105((R)-(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 3,4'-bi...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent