BDBM556717 US11352330, Example D33

SMILES CN(CCO)c1ncc2c(COc3cc(C)c(cc3C(C)(C)C)C#N)n[nH]c2n1

InChI Key InChIKey=USKGMLCKFACRFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556717   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM556717(US11352330, Example D33)
Affinity DataIC50: 6nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent