BDBM556522 N-(2-aminophenyl)-2-(3-(4-(((2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)propyl)oxazole-4-carboxamide TFA Salt::US11352322, Compound 153

SMILES Nc1ccccc1NC(=O)c1coc(CCCN2CCC(CNC3CC3c3ccccc3)CC2)n1

InChI Key InChIKey=NZNMKONNDJLCPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556522   

TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM556522(US11352322, Compound 153 | N-(2-aminophenyl)-2-(3-...)
Affinity DataIC50: 24nMAssay Description:LSD1 enzyme was produced in house. Tranylcypromine (TCP), LSD1 inhibitor was procured from Selleckchem. LSD1 enzyme, TCP and Biotinylated peptide sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM556522(US11352322, Compound 153 | N-(2-aminophenyl)-2-(3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Histone deacetylase assay was done as per manufacturer's instructions. Briefly, assay buffer, 200 uM HDAC substrate (fluorogenic HDAC acetylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent