BDBM556291 US11345702, Table 1.9::US20230390274, Compound A-36

SMILES COc1ccc(cc1Cl)-n1cnc2cc(ccc12)C(=O)N1CCCCC1

InChI Key InChIKey=QEPFIXNMGGOYSX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 556291   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Myoforte Therapeutics

US Patent
LigandPNGBDBM556291(US11345702, Table 1.9 | US20230390274, Compound A-...)
Affinity DataIC50: 47.1nMAssay Description:A hydroxyprostaglandin dehydrogenase inhibition screening biochemical assay can be performed to assess the synthesized inhibitors provided herein. Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
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Target5-hydroxytryptamine receptor 7(Human)
Epirium Bio

US Patent
LigandPNGBDBM556291(US11345702, Table 1.9 | US20230390274, Compound A-...)
Affinity DataIC50: 47.1nMAssay Description:The in vitro biochemical assay can be performed in white, 384 plates in total 20 μl reaction volume consisting of 10 nM of 15-PGDH/HPGD (R&D Sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 7(Human)
Epirium Bio

US Patent
LigandPNGBDBM556291(US11345702, Table 1.9 | US20230390274, Compound A-...)
Affinity DataIC50: 100nMAssay Description:The in vitro biochemical assay can be performed in white, 384 plates in total 20 μl reaction volume consisting of 10 nM of 15-PGDH/HPGD (R&D Sys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent