BDBM556176 US11345699, Example 60

SMILES C[C@H](CO)n1cnnc1-c1cccc(NC(=O)c2cc3CN(Cc4ccccn4)CCc3cn2)n1

InChI Key InChIKey=KFSXANXYMFBDJP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556176   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM556176(US11345699, Example 60)Copy SMILESCopy InChI

Affinity DataIC50: 1.25nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue #PV4011), ATP was purchased from Sigma (Catalogue #A7699), HTRF KinEASE Assay System was obtained fro...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2022
Entry Details
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