BDBM556145 US11345699, Example 30

SMILES CCNC(=O)N1CCc2cc(OC)c(cc2C1)C(=O)Nc1cccc(n1)-c1nnnn1C(C)C

InChI Key InChIKey=ZVDHDAQTNVTKAQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556145   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM556145(US11345699, Example 30)Copy SMILESCopy InChI

Affinity DataIC50: 1.25nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue #PV4011), ATP was purchased from Sigma (Catalogue #A7699), HTRF KinEASE Assay System was obtained fro...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2022
Entry Details
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