BDBM556127 US11345699, Example 12

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3CN(CCc3cc2F)c2ncccn2)n1

InChI Key InChIKey=XXIBXJTWRDAQPZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556127   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM556127(US11345699, Example 12)Copy SMILESCopy InChI

Affinity DataIC50: 1.25nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue #PV4011), ATP was purchased from Sigma (Catalogue #A7699), HTRF KinEASE Assay System was obtained fro...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/5/2022
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL