BDBM555712 US11345676, Compound 1-217::US11345676, Example 8

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2cc(Oc3ccncn3)ccc2F)n1

InChI Key InChIKey=QEHKWVVRWIAKKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555712   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555712(US11345676, Example 8 | US11345676, Compound 1-217)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent