BDBM555707 US11345676, Compound 1-24::US11345676, Example 3

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)c2cccc(Oc3cc(cc(n3)C(F)(F)F)C(O)=O)c2)n1

InChI Key InChIKey=MILNMAVEIBINOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555707   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555707(US11345676, Example 3 | US11345676, Compound 1-24)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
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