BDBM555582 5-Chloro-2-isobutyl-1-(2-methoxy-4-(((R)-1,1,1-trifluoropropan-2-yl)amino)phenyl)-N-(((1r,4R)-4-(methylsulfonyl)cyclohexyl)methyl)-1H-imidazole-4-carboxamide::US11345666, Example 9

SMILES COc1cc(N[C@H](C)C(F)(F)F)ccc1-n1c(Cl)c(nc1CC(C)C)C(=O)NC[C@H]1CC[C@@H](CC1)S(C)(=O)=O

InChI Key InChIKey=MZECXQYAUUSSMH-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555582   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM555582(5-Chloro-2-isobutyl-1-(2-methoxy-4-(((R)-1,1,1-tri...)
Affinity DataKd:  2.60nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent