BDBM555573 US11344553, Compound 2

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)ccc2F)CC1

InChI Key InChIKey=RUNUMABDVCXWMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555573   

TargetHigh affinity nerve growth factor receptor(Human)
Teligene

US Patent
LigandPNGBDBM555573(US11344553, Compound 2)
Affinity DataIC50: 1.80nMAssay Description:I. Prepare 1× Kinase Base Buffer and Stop Buffer for Testing Kinases1) 1× Kinase base buffer (for TRK-A)50 mM HEPES, pH 7.50.0015% Brij-352) Stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent