BDBM555282 3-((2,6-dichloro-1-(1-ethyl-1H-pyrazol-4-yl)-7-fluoro-1H-indol-3-yl)thio)-2-fluorobenzoic acid sodium salt ::US11344533, Compound 1-31

SMILES CCn1cc(cn1)-n1c(Cl)c(Sc2cccc(C(O)=O)c2F)c2ccc(Cl)c(F)c12

InChI Key InChIKey=JVJBBGAETSKIOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555282   

TargetAutotaxin(Human)
Sabre Therapeutics

US Patent
LigandPNGBDBM555282(US11344533, Compound 1-31 | 3-((2,6-dichloro-1-(1-...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetAutotaxin(Human)
Sabre Therapeutics

US Patent
LigandPNGBDBM555282(US11344533, Compound 1-31 | 3-((2,6-dichloro-1-(1-...)
Affinity DataIC50: 500nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent