BDBM555260 USRE49080, Example 36

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc3OCCC(O)c3c2)c1

InChI Key InChIKey=XRNTYSCFJIAWDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555260   

TargetSodium/glucose cotransporter 2(Human)
Novartis

US Patent
LigandPNGBDBM555260(USRE49080, Example 36)
Affinity DataIC50: 28nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent