BDBM555081 US11339151, Example 57

SMILES CCN(CCN1CCC(CC1)c1c[nH]c2ccccc12)S(=O)(=O)CCO

InChI Key InChIKey=VLXOYOJCCCNIRP-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 555081   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555081(US11339151, Example 57)
Affinity DataIC50: 6.20E+3nMAssay Description:Extracellular and intracellular fluids used in the measurement were prepared as follows.Extracellular fluid: 2 mmol/L CaCl2, 1 mmol/L MgCl2, 10 mmol/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555081(US11339151, Example 57)
Affinity DataKi:  1.60nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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Target5-hydroxytryptamine receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555081(US11339151, Example 57)
Affinity DataKi:  8.70nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetD(2) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555081(US11339151, Example 57)
Affinity DataKi:  210nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
Go to US Patent