BDBM555041 N-Ethyl-N-{2-[4-(6-fluoro-1,2-benzoisoxazol-3-yl)piperidin-1-yl]ethyl}-3-hydroxypropanamide::US11339151, Example 17

SMILES CCN(CCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)CCO

InChI Key InChIKey=APSSHASNQVGROU-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 555041   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555041(US11339151, Example 17 | N-Ethyl-N-{2-[4-(6-fluoro...)
Affinity DataIC50: 2.80E+3nMAssay Description:Extracellular and intracellular fluids used in the measurement were prepared as follows.Extracellular fluid: 2 mmol/L CaCl2, 1 mmol/L MgCl2, 10 mmol/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555041(US11339151, Example 17 | N-Ethyl-N-{2-[4-(6-fluoro...)
Affinity DataKi:  0.800nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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Target5-hydroxytryptamine receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555041(US11339151, Example 17 | N-Ethyl-N-{2-[4-(6-fluoro...)
Affinity DataKi:  4.90nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetD(2) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555041(US11339151, Example 17 | N-Ethyl-N-{2-[4-(6-fluoro...)
Affinity DataKi:  155nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
Go to US Patent