BDBM554735 US11337976, Compound P-0233

SMILES CC(N(C)C)S(=O)(=O)Nc1cccc(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(nc2)C2CC2)c1F

InChI Key InChIKey=GRPVPCGDHMYVMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554735   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Plexxikon

US Patent
LigandPNGBDBM554735(US11337976, Compound P-0233)
Affinity DataIC50: 100nMAssay Description:For example, the biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent