BDBM554652 US11339144, Compound I-102

SMILES CN(C)C(=O)c1ccc(cc1)Cn2c3cc(cc(c3cc2C(=O)O)Br)Sc4ccc(c(c4)Cl)Cl

InChI Key InChIKey=MJYFVDNMTKLGTH-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554652   

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554652(US11339144, Compound I-102)
Affinity DataIC50: 1.00E+4nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
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PDB3D3D Structure (crystal)