BDBM554633 US11339144, Compound I-86

SMILES OC(=O)c1cc2c(Sc3ccc(cc3)C(F)(F)F)cc(Cl)cc2[nH]1

InChI Key InChIKey=GXCRBFXMJMMGDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554633   

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554633(US11339144, Compound I-86)
Affinity DataIC50: 1.00E+4nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
Go to US Patent